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Cover of Pathogenic

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Games like Pathogenic

2026PC, Steam Deck verified93 % positive9.99 €

A roguelike shooter where you play as a pathogen invading the human body, evolving your parasite with collected organelles. You fight the host's immune system across procedurally generated microscopic environments.

  • Runs that play out differently every time
  • Build variety
  • Loot and gear
  • Shooting and gunplay
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Where to buy

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More in these topics: Roguelikes and roguelites Action games Hidden gems Indie games

In short: Games like Pathogenic

Each of these 10 games shares something of what makes Pathogenic special. The reasons are listed right on each game.

Similar in what way?

0 of 3

Up to three areas count more, the rest steps back.

Not for me Exclude horror, turn-based combat, pixel art …

Games where this is clearly part of it are left out, no matter how well the rest fits.

Horror Turn-based combat High difficulty Roguelike runs Shooter Pixel art Grind Survival PvP Open world Card game

10 games with a similar feel, sorted by match · How is this calculated?

Show games from the same series

Best match

Deep Rock Galactic: Survivor

94 %Match

2025PC, PlayStation, Xbox, Nintendo Switch, Steam Deck verified86 % positive12.99 €

Brings what grabs you about Pathogenic: runs that differ every time, lots of builds to try as well as hunting for loot and gear.

A survivor-like set in the Deep Rock universe where a lone dwarf auto-shoots through alien swarms while carving through destructible rock for minerals. Synergizing weapon upgrades and persistent unlocks deliver that one-more-run pull.

Where to buy

* Affiliate link. Prices are synced regularly and may have changed in the shop since.

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Everspace

Runs that play out differently every time

A fast-paced space shooter with full 6DOF flight where every death starts a new run with permanent upgrades. Intense dogfights, scavenging and gorgeous sci-fi vistas drive the experience.

Gunfire Reborn

Runs that play out differently every time

A fast-paced roguelite first-person shooter where you fight through procedurally generated levels alone or with up to three friends, crafting varied builds from heroes, weapons and upgrades.

Beacon

Shooting and gunplay

Beacon is a top-down sci-fi shooter where you fight through a randomly generated hostile planet to find your distress beacon. Each death lets you recombine DNA harvested from enemies, so every run makes your next attempt stronger.

Deadlink

Shooting and gunplay

A fast cyberpunk first-person shooter with roguelite structure where you pilot a remote combat shell through corporate strongholds. Fluid movement, destructible environments and upgrades between runs drive the pace and replayability.

Juicy Realm

Shooting and gunplay

A fast top-down roguelike shooter where you play a soldier blasting through randomized levels full of mutated, hostile fruit. Plenty of weapons, upgrades and a bright, cartoonish look make for quick, varied runs.

Roboquest

Runs that play out differently every time

A fast, colorful roguelite FPS where you play a rebooted robot Guardian and blast hordes of machines through shifting levels, solo or in co-op. Fluid movement, varied weapons and classes make every run feel different.

Tower of Guns

Runs that play out differently every time

A fast bullet-hell first-person shooter with randomly generated towers, huge bosses, and absurdly stackable weapons and upgrades. Its roguelike structure makes every run feel different.

Soul Knight

Shooting and gunplay

A fast pixel-art roguelike shooter where you blast through randomly generated dungeons, collect wacky weapons and dodge bullets. Simple controls and a large roster of heroes make it ideal for quick runs, including co-op.

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