Cover of Pathogenic

Similar games

Games like Pathogenic

2026PC, Steam Deck verified93 % positive9.99 €

A roguelike shooter where you play as a pathogen invading the human body, evolving your parasite with collected organelles. You fight the host's immune system across procedurally generated microscopic environments.

  • Runs that play out differently every time
  • Build variety
  • Loot and gear
  • Shooting and gunplay

Where to buy

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In short: Games like Pathogenic

Each of these 10 games shares something of what makes Pathogenic special. The reasons are listed right on each game.

Similar in what way?

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Up to three areas count more, the rest steps back.

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Not for me Exclude horror, turn-based combat, pixel art …

Games where this is clearly part of it are left out, no matter how well the rest fits.

10 games with a similar feel, sorted by match · How is this calculated?

Best match

Everspace

91 %Match

2017USK 12PC, PlayStation, Xbox, Steam Deck playable77 % positive−90 % 19.99 € 1.99 €

Brings what grabs you about Pathogenic: runs that differ every time, hunting for loot and gear as well as lots of builds to try.

A fast-paced space shooter with full 6DOF flight where every death starts a new run with permanent upgrades. Intense dogfights, scavenging and gorgeous sci-fi vistas drive the experience.

Where to buy

  • Steam PC · until tomorrow 1.99 € 19.99 € −90 % Go to shop
  • Gamesplanet* Steam key · 4 days left 1.99 € 19.99 € −90 % Go to shop
  • Amazon* Price in shop PlayStation Xbox

* Affiliate link. Prices are synced regularly and may have changed in the shop since.

Galactic Glitch

Shooting and gunplay

A roguelike shooter built around physics: hurl rocks, catch missiles and turn torn-apart enemies into ammo. You craft your own build from many weapons and powers while exploring a simulated universe.

Jydge

Loot and gear

A roguelike-flavored top-down shooter where you build a cybernetic judge and enforce brutal law across the megacity of Edenbyrg. Fast gunfights and character building meet a grim, satirical cyberpunk setting.

Sublevel Zero: Redux

Loot and gear

A roguelike six-degrees-of-freedom shooter in the spirit of Descent: you pilot a gunship through procedurally generated zero-gravity facilities, fighting enemies and looting tech to craft upgrades.

Sulfur

Loot and gear

A retro-flavored first-person shooter with roguelike elements: you push through procedurally built levels, collect loot, upgrade weapons and use special powers. A grim mood and the search for answers pull you ever deeper.

Deflector

Shooting and gunplay

A fast-paced bullet hell roguelite where you upgrade characters with collected DNA and evolve them during runs. Dodging and quick reflexes are at the heart of the experience.

Wall World 2

Strong character progression

You drive a giant robotic spider up an endless wall, alternating between mining and fighting off threats in your exosuit. Between runs you permanently upgrade the spider and your gear while slowly uncovering the wall's secrets.

Sky Rogue

Shooting and gunplay

In Sky Rogue you fly through an endless chain of procedurally generated islands, dogfighting enemy aces and assaulting giant carriers. Death is permanent, so every sortie feels tense and arcadey.

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