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Games like Big Pharma

2015PC, PlayStation, Xbox, Nintendo Switch, Steam Deck playable78 % positive24.50 €

A factory-optimization business sim where you design production lines for drugs, tune ingredients and layouts, and balance efficacy, side effects and profit. A wry, distinctive art style accompanies the satisfying puzzle-like tinkering.

  • Economy and management
  • Puzzles and brain teasers
  • Tactical depth
  • Lots of humour
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Where to buy

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More in these topics: Puzzle games

In short: Games like Big Pharma

Each of these 10 games shares something of what makes Big Pharma special. The reasons are listed right on each game.

Similar in what way?

0 of 3

Up to three areas count more, the rest steps back.

Not for me Exclude horror, turn-based combat, pixel art …

Games where this is clearly part of it are left out, no matter how well the rest fits.

Horror Turn-based combat High difficulty Roguelike runs Shooter Pixel art Grind Survival PvP Open world Card game

10 games with a similar feel, sorted by match · How is this calculated?

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Best match

Two Point Hospital

96 %Match

2018USK 0PC, PlayStation, Xbox, Nintendo Switch, Steam Deck playable92 % positive29.99 €

Brings what grabs you about Big Pharma: economy and management, plenty of humour as well as tactical depth.

A humorous hospital management sim where you cure absurd illnesses, lay out efficient rooms and keep staff happy. Witty British humor and charming details make building and optimizing a joy.

Where to buy

* Affiliate link. Prices are synced regularly and may have changed in the shop since.

Similar games →

Prison Architect

Distinctive, stylised art style

A deep construction and management sim where you design a prison from scratch, hire staff and keep inmates from rioting or escaping. Its cute, simple art style contrasts with darkly humorous takes on serious themes like violence and the death penalty.

Little Big Workshop

Calm and deliberate

A charming factory tycoon sim where you lay out production lines in a miniature world, expand machines and workers, and sell goods from rubber ducks to guitars. Relaxed optimization is the core.

Megaquarium

Calm and deliberate

A management sim where you build and run a large public aquarium: you design tanks, match compatible fish, hire staff and keep visitors happy. Its appeal lies in puzzling over species needs and water conditions within a relaxed, charming building loop.

Minami Lane

Calm and deliberate

A relaxing small-scale management game where you design a Japanese-inspired street, run its shops and keep the residents happy. It offers short goal-driven levels plus a freeform sandbox mode.

Reus

Puzzles and brain teasers

You play a god commanding four giants who raise mountains, oceans and forests to help tiny human villages flourish. Placing and combining plants, animals and minerals makes for a puzzle-like planning game where humans never do quite what you want.

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